1.
Indian Pediatr
;
2015 Nov; 52(11): 981-983
Article
in English
| IMSEAR
| ID: sea-172285
ABSTRACT
Background: 3β-hydroxysteroid dehydrogenase type II deficiency results in decreased production of all three groups of adrenal steroids. Recurrent hypoglycemia as a presenting feature of this disorder has not been reported earlier. Case characteristics: A genotypically and phenotypically normal female newborn delivered by in-vitro fertilization presenting with recurrent hypoglycemia. Primary adrenal insufficiency with insignificant mineralocorticoid deficiency and slightly elevated levels of 17-hydro-xyprogesterone, dehydroepiandrosterone sulphate and testosterone. Outcome: Successfully managed only with corticosteroid replacement. Message: Congenital adrenal hyperplasia can rarely cause recurrent hypoglycemia in newborns.